Journal of Sensors and Sensor Systems
Journal of Sensors and Sensor Systems
JSSS
Articles | Volume 5, issue 1
Articles | Volume 5, issue 1
https://doi.org/10.5194/jsss-5-221-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
Special issue:
https://doi.org/10.5194/jsss-5-221-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
Articles | Volume 5, issue 1
Regular research article
 | 
24 Jun 2016
Regular research article |  | 24 Jun 2016

Design, characterization, and modeling of microcirculation systems with integrated oxygenators

Mathias Busek, Stefan Gruenzner, Tobias Steege, Florian Schmieder, Udo Klotzbach, and Frank Sonntag

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Short summary
A novel cell-cultivation platform with small circulating volume and included oxygen controlling system is presented. This system may be used to investigate the influence of oxygen restriction, called hypoxia, to cultivated human cells and therefore helps to reduce animal testing in this field of research. Furthermore, a mathematic model of the oxygen transport is presented which may be utilized to produce well-defined oxygen microenvironments.
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Special issue
Dresden Sensor Symposium 2015