Articles | Volume 5, issue 1
J. Sens. Sens. Syst., 5, 221–228, 2016
https://doi.org/10.5194/jsss-5-221-2016

Special issue: Dresden Sensor Symposium 2015

J. Sens. Sens. Syst., 5, 221–228, 2016
https://doi.org/10.5194/jsss-5-221-2016

Regular research article 24 Jun 2016

Regular research article | 24 Jun 2016

Design, characterization, and modeling of microcirculation systems with integrated oxygenators

Mathias Busek et al.

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Cited articles

Abid, H. J., Chen, J., and Nassar, A. A.: Equivalent Air Spring Suspension Model for Quarter-Passive Model of Passenger Vehicles, International Scholarly Research Notices, 2015, 1–6, https://doi.org/10.1155/2015/974020, 2015.
Abramowitz, M. and Stegun, I. A.: Handbook of mathematical functions: With formulas, graphs, and mathematical tables, Dover books on mathematics, Dover Publications, New York, USA, XIV, 1046, 1970.
Ataç, B., Wagner, I., Horland, R., Lauster, R., Marx, U., Tonevitsky, A. G., Azar, R. P., and Lindner, G.: Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion, Lab Chip, 13, 3555–3561, https://doi.org/10.1039/c3lc50227a, 2013.
Baker, M.: Tissue models: a living system on a chip, Nature, 471, 661–665, https://doi.org/10.1038/471661a, 2011.
Bhatia, S. N. and Ingber, D. E.: Microfluidic organs-on-chips, Nature biotechnology, 32, 760–772, https://doi.org/10.1038/nbt.2989, 2014.
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Short summary
A novel cell-cultivation platform with small circulating volume and included oxygen controlling system is presented. This system may be used to investigate the influence of oxygen restriction, called hypoxia, to cultivated human cells and therefore helps to reduce animal testing in this field of research. Furthermore, a mathematic model of the oxygen transport is presented which may be utilized to produce well-defined oxygen microenvironments.