Articles | Volume 8, issue 1
https://doi.org/10.5194/jsss-8-215-2019
https://doi.org/10.5194/jsss-8-215-2019
Regular research article
 | 
21 May 2019
Regular research article |  | 21 May 2019

Optical and impedimetric study of genetically modified cells for diclofenac sensing

Margarita Guenther, Falko Altenkirch, Kai Ostermann, Gerhard Rödel, Ingo Tobehn-Steinhäuser, Steffen Herbst, Stefan Görlandt, and Gerald Gerlach

Viewed

Total article views: 4,211 (including HTML, PDF, and XML)
HTML PDF XML Total Supplement BibTeX EndNote
3,705 461 45 4,211 206 47 43
  • HTML: 3,705
  • PDF: 461
  • XML: 45
  • Total: 4,211
  • Supplement: 206
  • BibTeX: 47
  • EndNote: 43
Views and downloads (calculated since 21 May 2019)
Cumulative views and downloads (calculated since 21 May 2019)

Viewed (geographical distribution)

Total article views: 3,271 (including HTML, PDF, and XML) Thereof 3,083 with geography defined and 188 with unknown origin.
Country # Views %
  • 1
1
 
 
 
 

Cited

Latest update: 02 Jul 2024
Download
Short summary
In this work, genetically modified cells of the yeast Saccharomyces cerevisiae BY4741 were confined in a four-chamber microfluidic cell, providing an optical monitoring of the cell behaviour and their supply with the nutrients. The measurements of the time-dependent fluorescence intensity were performed with different concentrations of the drug diclofenac, and the sensitivity of yeast cells to diclofenac was demonstrated. Cell viability was monitored by simultaneous impedance recording.