Articles | Volume 7, issue 2
https://doi.org/10.5194/jsss-7-559-2018
https://doi.org/10.5194/jsss-7-559-2018
Regular research article
 | 
29 Oct 2018
Regular research article |  | 29 Oct 2018

Continuous in-line monitoring of electrolyte concentrations in extracorporeal circuits for individualization of dialysis treatment

Marc Berger, Michael Faulstich, Thorsten Perl, and Stefan Zimmermann

Cited articles

Bagshaw, S. M., George, C., and Bellomo, R.: Early acute kidney injury and sepsis: A multicentre evaluation, Crit. Care, 12, R47, https://doi.org/10.1186/cc6863, 2008. 
Baue, A. E., Faist, E., and Fry, D. E.: Multiple Organ Failure: Pathophysiology, Prevention, and Therapy, N, Springer New York, New York, 1, online resource 722, 2000. 
Bellomo, R., Kellum, J. A., and Ronco, C.: Acute kidney injury, The Lancet, 380, 756–766, https://doi.org/10.1016/S0140-6736(11)61454-2, 2012. 
Buemi, M., Aloisi, E., Coppolino, G., Loddo, S., Crascì, E., Aloisi, C., Barillà, A., Cosentini, V., Nostro, L., Caccamo, C., Floccari, F., Romeo, A., Frisina, N., and Teti, D.: The effect of two different protocols of potassium haemodiafiltration on QT dispersion, Nephrol. Dial. Transpl., 20, 1148–1154, https://doi.org/10.1093/ndt/gfh770, 2005. 
Bundesärztekammer: Richtlinie der Bundesärztekammer zur Qualitätssicherung laboratoriumsmedizinischer Untersuchungen, Deutsches Ärzteblatt, 111, A 1583–A 1618, 2014. 
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Short summary
A dialysis treatment with an individual dialysis fluid composition can prevent certain complications during treatment. For this purpose, it is necessary to know the exact electrolyte concentrations in the blood. In this work, we present a concept for continuous in-line monitoring of electrolyte concentrations using ion-selective electrodes separated from the blood flow by a dialysis membrane. First investigations of this concept show no hemolysis and a relative error of less than 0.5 %.
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