Journal of Sensors and Sensor Systems
Journal of Sensors and Sensor Systems
JSSS
Articles | Volume 13, issue 2
Articles | Volume 13, issue 2
https://doi.org/10.5194/jsss-13-245-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jsss-13-245-2024
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 13, issue 2
Regular research article
 | 
10 Dec 2024
Regular research article |  | 10 Dec 2024

A portable biosensor for simultaneous diagnosis of TNF-α and IL-1β in saliva biomarkers using twin electronic devices

Majid Monajjemi, Fatemeh Mollaamin, Motahareh Dehghandar, Sara Shahriari, Parisa Latifi, and Samira Mohammadi

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Latest update: 28 Oct 2025
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Short summary
We present a sensor platform that can detect the oral cancer signature of biomarkers in saliva. This system works by arraying metal–oxide–semiconductor field-effect transistors (MOSFETs) and electrolyte-gated transistors (EGTs), with each targeting a biorecognition element (BRE) from a DNA sequence found in the promoter region of most biomarker genes. This system is also applicable to the simultaneous diagnosis of TNF-α and IL-1β immune-modulator biomarkers.
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