Articles | Volume 7, issue 2
https://doi.org/10.5194/jsss-7-461-2018
https://doi.org/10.5194/jsss-7-461-2018
Regular research article
 | 
08 Aug 2018
Regular research article |  | 08 Aug 2018

Development and characterisation of a new fluorescence sensor for online monitoring of bioprocesses

Jan C. König, Tobias Steinwedel, Dörte Solle, Patrick Lindner, Ingo de Vries, Thorleif Hentrop, Michael Findeis, Gernot T. John, Thomas Scheper, and Sascha Beutel

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Latest update: 28 Mar 2024
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Short summary
Fluorescence spectroscopy represents a very sensitive method, but fluorescence sensors are mainly used in academia and rarely in industrial processes. In this work, we present a newly developed functional model of an online fluorescence sensor. The sensor was miniaturised and constructed without any movable parts to detect important biologic fluorophores. Its performance was evaluated by calibration curves and selectivity tests and it was used for a biomass prediction of E. coli cultivations.