Articles | Volume 11, issue 1
https://doi.org/10.5194/jsss-11-117-2022
https://doi.org/10.5194/jsss-11-117-2022
Regular research article
 | 
08 Apr 2022
Regular research article |  | 08 Apr 2022

Acoustophoresis in suspensions with local and time-discrete sound fields based on the time reversal technique

Philipp Hörnlein, Sebastian Wöckel, Hendrik Arndt, and Jörg Auge

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Cited articles

Antfolk, M., Kim, S. H., Koizumi, S., Fujii, T., and Laurell, T.: Label-free single-cell separation and imaging of cancer cells using an integrated microfluidic system, Sci. Rep., 7, 1–12, https://doi.org/10.1038/srep46507, 2017. 
Augustsson, P., Barnkob, R., Grenvall, C., Deierborg, T., Brundin, P., Bruus, H., and Laurell, T.: Measuring the acoustophoretic contrast factor of living cells in microchannels, in: Proceedings of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences, 3–7 October 2010, Groningen, the Netherlands, 1337–1339, 2010. 
Baudoin, M., Gerbedoen, J.-C., Riaud, A., Matar, O.-B., Smagin, N., and Thomas, J.-L.: Folding a focalized acoustical vortex on a flat holographic transducer: Miniaturized selective acoustical tweezers, Science Advances, 5, 1–7, https://doi.org/10.1126/sciadv.aav1967, 2019. 
Cassereau, D. and Fink, M.: Time-Reversal of Ultrasonic Fields – Part III: Theory of the Closed Time-Reversal Cavity, IEEE T. Ultrason. Ferr., 39, 579–592, https://doi.org/10.1109/58.156176, 1992. 
Chitale, K. C., Presz, W., Ross-Johnsrud, B. P., Hyman, M., Lamontagne, M., and Lipkens, B.: Particle manipulation using macroscale angled ultrasonic standing waves, in: Proceedings of Meetings on Acoustics, Acoustical Society of America 173rd Meeting of Acoustical Society of America and 8th Forum Acusticum, Boston, 25–29 June 2017, 045004, https://doi.org/10.1121/2.0000652, 2017. 
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Short summary
The present research work investigated the acoustic manipulation of bioparticles and cells in closed and liquid-filled vessels using a special method for focusing acoustic fields. Based on simulation studies, the feasibility of particle manipulation with this method was successfully demonstrated. Successful final testing using a demonstrator and thus the transfer and prospective application in biotechnology are part of further research work.